This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq]
应用类型
该BubB1B（BubR1）产品的应用类型详情查看产品说明书。
免疫原
Full length human recombinant protein of human BUB1B (NP_001202) produced in HEK293T cell.
