Rho guanine nucleotide exchange factor 10(ARHGEF10) Homo sapiens This gene encodes a Rho guanine nucleotide exchange factor (GEF). Rho GEFs regulate the activity of small Rho GTPases by stimulating the exchange of guanine diphosphate (GDP) for guanine triphosphate (GTP) and may play a role in neural morphogenesis. Mutations in this gene are associated with slowed nerve conduction velocity (SNCV). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015],
应用类型
WB,IHC,IF,ELISA
免疫原
The antiserum was produced against synthesized peptide derived from human ARHGEF10. AA range:339-388
