This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.
应用类型
该抗NTRK3（TrkC）产品的应用类型详情查看产品说明书。
免疫原
Full-length protein expressed in 293T cell transfected with human NTRK3 expression vector
