DOCK 180, a 180 kDa protein downstream of Crk, has been identified as a major Crk-associated protein. When DOCK 180 is recruited to the plasma membrane from a cytoplasmic reservoir, presumably by Crk, changes in cellular morphology and spindle formation occur, suggesting DOCK 180 to be a Crk effector molecule
应用类型
WB,IHC
免疫原
Synthetic peptide, corresponding to amino acids 1660-1719 of Human DOCK 180.
