The vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles,using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine
应用类型
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免疫原
Full-length protein expressed in 293T cell transfected with human SLC18A2 expression vector