- 中文名称
DUT
- 英文名字
- DUT
- 供应商
- Nordic BioSite
- 产品货号
- NDC-BT-QLEN9C-50
- 产品报价
- ￥询价/50ul
- 产品说明书
- 点击查看
- 购买方式
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- 产品新闻
- 背景资料
- dUTPase (deoxyuridine 5’-triphosphate nucleotidohydrolase), also known as DUT or dUTP pyrophosphatase, is a preventive DNA repair enzyme that functions in nucleotide metabolism. dUTPase is expressed in a variety of tissues and, depending on the isoform (DUT-N or DUT-M), localizes to the nucleus or the mitochondrion. The nuclear isoform, DUT-N, is the most abundant of the two isoforms. dUTPase, in the presence of magnesium ions, is responsible for hydrolyzing dUTP to dUMP and diphosphate. This reaction is important for keeping the intracellular dUTP concentration low so that uracil does not become incorporated into DNA. Extensive incorporation of uracil into DNA can ultimately lead to cell death. This suggests that dUTPase is essential for cell viability, further implying that dUTPase is a potential target for anticancer therapy. In addition, dUMP, the product of the hydrolysis reaction, is a precursor of thymidine nucleotides which are essential for DNA replication.
- 应用类型
- WB
- 免疫原
- Recombinant full length Human DUT.
- 来源宿主
- 该Anti-ACCS antibody (222-501)产品的来源宿主详情查看产品说明书。
- 反应性
- BT-QLEN9C-50
- 保存建议
- human
- 其他
- Nordic BioSite(北欧生物) 总部位于瑞典，成立于1997年，旨在分销研究和诊断领域的高质量和创新产品。 Nordic BioSite 被公认为整个北欧生物医学研究和诊断产品领域的领导者。他们拥有超过570万种的产品组合，代理了遍布欧洲和美国的顶级生物试剂制造商，是欧洲知名的一站式生物试剂代理商。除了作为分销商之外，Nordic BioSite 还拥有不断增长的自产产品线——BioSite mAb、BioSite ELISA、BioSite Flow、Optibodies和 BioSite Protein, 目前艾美捷代理的是Nordic BioSite自产产品线(共26W+产品)。Nordic BioSite的产品类型主要是抗体，蛋白和试剂盒，产品适用范围涵盖15个不同的物种(人，牛，犬，鲶鱼，鸡，海豚，马，猫，豚鼠，小鼠，绵羊，兔子，大鼠，猪和火鸡)，可为您提供一站式的生命科学研究解决方案~
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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