Stat4 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells.
应用类型
该抗Stat4产品的应用类型详情查看产品说明书。
免疫原
Recombinant fragment expressed in E.coli corresponding to amino acids 633-652 of human Stat4