EF-1 (elongation factor-1) is a multi-protein complex that is responsible for the delivery of aminoacyl-tRNAs to the ribosome. The EF-1 protein complex is composed of four subunits: EF-1 α, EF-1 β, EF-1 δ and EF-1 γ. EF-1 β is a 225 amino acid member of the EF-1 β/EF-1 δ protein family and contains one GST C-terminal domain. Both EF-1 β and EF-1 δ stimulate the exchange of GDP bound to EF-1 α to GTP. Phosphorylation of EF-1 β affects the GDP/GTP exchange rate. Alternative splicing events of the gene that encodes EF-1 β result in three transcript variants that differ only in the 5' UTR.
应用类型
WB
免疫原
Synthetic peptide, corresponding to amino acids 142-187 of Human EEF1B2.
