Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair. [provided by RefSeq, Jul 2008]
应用类型
该CHAF1B产品的应用类型详情查看产品说明书。
免疫原
Full length human recombinant protein of human CHAF1B(NP_005432) produced in HEK293T cell.
来源宿主
mouse
反应性
该Mouse Monoclonal Antibody to CHRNA10产品的反应性详情查看产品说明书。