- 中文名称
FR beta
- 英文名字
- FR beta
- 供应商
- Nordic BioSite
- 产品货号
- NDC-BT-K82FGY-100
- 产品报价
- ¥询价/100ul

- 产品说明书
- 点击查看
- 购买方式
- 90%产品中国有现货库存。银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868
- 产品新闻

- 背景资料
- FR beta(FR beta),详情产看产品说明书
- 序列
- Folate is an essential vitamin that must be obtained from food intake through intestinal absorption in mammals. Folate and reduced folic acid derivatives bind to the folate receptor (FR) family, which mediates the endocytosis of 5-methyltetrahydofolate into the cell. The folate receptors consist of five members, α, β, γ, γ' (which is produced by alternative splicing) and δ. α-FR and β-FR are attached to the membrane by a GPI anchor and are expressed in malignant tissues of epithelial and nonepithelial origin, respectively. γ-FR is expressed in tissues of hematopoietic origin, such as spleen, thymus and bone marrow, but the expression pattern of δ-FR is elusive, which suggests that it is highly restricted both spatially and temporally. α-FR is used as a highly selective tumor marker and may be targeted for the delivery of therapeutic compounds to tumor cells by coupling to derivatives of folic acid.
- 来源宿主
- Folate is an essential vitamin that must be obtained from food intake through intestinal absorption in mammals. Folate and reduced folic acid derivatives bind to the folate receptor (FR) family, which mediates the endocytosis of 5-methyltetrahydofolate into the cell. The folate receptors consist of five members, α, β, γ, γ' (which is produced by alternative splicing) and δ. α-FR and β-FR are attached to the membrane by a GPI anchor and are expressed in malignant tissues of epithelial and nonepithelial origin, respectively. γ-FR is expressed in tissues of hematopoietic origin, such as spleen, thymus and bone marrow, but the expression pattern of δ-FR is elusive, which suggests that it is highly restricted both spatially and temporally. α-FR is used as a highly selective tumor marker and may be targeted for the delivery of therapeutic compounds to tumor cells by coupling to derivatives of folic acid.
- 溶解建议
- WB: 1:500~1:1000
IHC: 1:50~1:200
- 保存建议
- Store at 4
- 其他
- Nordic BioSite(北欧生物) 总部位于瑞典,成立于1997年,旨在分销研究和诊断领域的高质量和创新产品。 Nordic BioSite 被公认为整个北欧生物医学研究和诊断产品领域的领导者。他们拥有超过570万种的产品组合,代理了遍布欧洲和美国的顶级生物试剂制造商,是欧洲知名的一站式生物试剂代理商。除了作为分销商之外,Nordic BioSite 还拥有不断增长的自产产品线——BioSite mAb、BioSite ELISA、BioSite Flow、Optibodies和 BioSite Protein, 目前艾美捷代理的是Nordic BioSite自产产品线(共26W+产品)。Nordic BioSite的产品类型主要是抗体,蛋白和试剂盒,产品适用范围涵盖15个不同的物种(人,牛,犬,鲶鱼,鸡,海豚,马,猫,豚鼠,小鼠,绵羊,兔子,大鼠,猪和火鸡),可为您提供一站式的生命科学研究解决方案~

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