The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear proteins that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730)and interact with RNA polymerase to activate or repress transcription. The proteins LMX1 (MIM600298) and CDX3 are homeodomain proteins that bind an A/T-rich sequence in the insulin promoter and stimulate its transcription.
应用类型
该抗CDX2抗体产品的应用类型详情查看产品说明书。
免疫原
Recombinant protein expressed in E.coli corresponding to amino acids 1-313 of human CDX2
