Collapsin response mediator proteins (CRMPs), including CRMP-1 (DRP-1), CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-4 (DRP-3) and CRMP-5 (DRP-5), mediate signal transduction after exposure of neural cells to the axon guidance molecule Semaphorin 3A (SEMA3A)/collapsin. CRMPs are present in the developing cerebral cortex and neocortical neurons and are responsive to SEMA3A. In the adult brain, the expression of CRMPs is dramatically downregulated. However, they remain expressed in structures that retain their capacity for differentiation and plasticity. CRMP-3 is expressed transiently in developing spinal cord and selectively in the postnatal cerebellum.
应用类型
该CRMP-3 (C132)产品的应用类型详情查看产品说明书。
免疫原
Synthetic peptide, corresponding to amino acids 111-160 of Human CRMP-3.
来源宿主
rabbit
反应性
该Rabbit IgG polyclonal antibody for Collagen II detection. Tested with WB in Human;Mouse;Rat.产品的反应性详情查看产品说明书。
