The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
应用类型
该ATG16L1基因产品的应用类型详情查看产品说明书。
免疫原
Human recombinant protein fragment corresponding to amino acids 1-277 of human ATG16L (NP_110430) produced in E.coli.
