This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene
应用类型
该抗NTRK2(TrkB)产品的应用类型详情查看产品说明书。
免疫原
Full-length protein expressed in 293T cell transfected with human NTRK2 expression vector