- 中文名称
EIF2AK1 polyclonal antibody
- 英文名字
- EIF2AK1 polyclonal antibody
- 供应商
- Nordic BioSite
- 产品货号
- NDC-BT-4E1E1B
- 产品报价
- ￥询价/50ul
- 产品说明书
- 点击查看
- 购买方式
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- 产品新闻
- 背景资料
- HRI (heme-regulated inhibitor kinase) phosphorylates the α subunit of eIF2α kinase, which plays an important role in translational regulation during heme deficiency. HRI is activated in response to a number of environmental conditions, including heme deficiency, heat shock, and oxidative stress. Autophosphorylation is essential for the activation of HRI, which causes an arrest of initiation of protein synthesis. Both HSP 90 and HSC 70 are necessary for all stress-induced HRI activation. Furthermore, HSC 70 is required for the folding and transformation of HRI into an active kinase and is subsequently required to negatively attenuate the activation of transformed HRI. Both the N-terminus and the kinase insertion domain, which are unique to HRI, are involved in the heme binding and the heme regulation of HRI. The human HRI gene maps to chromosome 7p22.1 and encodes a 630 amino acid protein expressed mainly in erythroid cells.
- 应用类型
- WB
- 免疫原
- Synthetic peptide, corresponding to amino acids 580-630 of Human EIF2AK1.
- 来源宿主
- rabbit
- 反应性
- human,mouse,rat
- 保存建议
- Store at 4
- 其他
- Nordic BioSite(北欧生物) 总部位于瑞典，成立于1997年，旨在分销研究和诊断领域的高质量和创新产品。 Nordic BioSite 被公认为整个北欧生物医学研究和诊断产品领域的领导者。他们拥有超过570万种的产品组合，代理了遍布欧洲和美国的顶级生物试剂制造商，是欧洲知名的一站式生物试剂代理商。除了作为分销商之外，Nordic BioSite 还拥有不断增长的自产产品线——BioSite mAb、BioSite ELISA、BioSite Flow、Optibodies和 BioSite Protein, 目前艾美捷代理的是Nordic BioSite自产产品线(共26W+产品)。Nordic BioSite的产品类型主要是抗体，蛋白和试剂盒，产品适用范围涵盖15个不同的物种(人，牛，犬，鲶鱼，鸡，海豚，马，猫，豚鼠，小鼠，绵羊，兔子，大鼠，猪和火鸡)，可为您提供一站式的生命科学研究解决方案~
- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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