Adipocyte enhancer-binding protein 2 (AEBP2), also known as zinc finger protein AEBP2, is an 817 amino acid member of the AEBP2 C2H2-type zinc-finger protein family. Localized to the nucleus, AEBP2 acts as a DNA-binding transcriptional repressor of the adipose P2 (aP2) gene. The aP2 gene, which encodes the adipose fatty acid-binding protein, plays a critical role in triglyceride metabolism during adipocyte differentiation. The AE-1 region in the proximal promoter region of the aP2 gene functions as either a positive or negative regulatory element. C/EBP
