Androgens exhibit a wide range of effects on the development, maintenance and regulation of male phenotype and reproductive physiology in males. The androgen receptor (AR) is a member of the steroid superfamily of ligand-dependent transcription factors. ARs bind active testosterone (T) and dihydrotestosterone (DHT). The rates of association and dissociation of T are about 3 times more rapid than those of DHT. This difference in binding kinetics may account for the different physiological effects of T and DHT. Androgen binding results in an at least 6-fold increase in androgen receptor stability.
应用类型
该AR (phospho-Y363)产品的应用类型详情查看产品说明书。
免疫原
Synthetic phosphopeptide derived from human AR around the phosphorylation site of Tyrosine 363.
来源宿主
rabbit
反应性
该Rabbit IgG polyclonal antibody for ANAPC2 detection. Tested with WB, IHC, ICC/IF, FCM, Direct ELISA in Human;Mouse;Rat;Monkey.产品的反应性详情查看产品说明书。
