The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome.
应用类型
IF,WB
免疫原
A synthetic peptide corresponding to a sequence within amino acids 79-129 of human CD40L (NP_000065.1).
