Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition, Involved in the histone 3' end pre-mRNA processing.
应用类型
WB
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 450-700 of human CPSF2 (NP_059133.1).
