Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated, As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3, May function as a transcriptional regulator, May play a role in hematopoiesis.
应用类型
IF
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 235-534 of human ASH2L (NP_001098684.1).
