Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation, Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle, Cycles between a juxta-nuclear trans-Golgi network compartment and late endosomes, Nutrient starvation induces accumulation on autophagosomes, Starvation-dependent trafficking requires ULK1, ATG13 and SUPT20H.
应用类型
IF,WB
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 180-290 of human ATG9A (NP_076990.4).