Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation, Can also repair alkylated DNA containing 1-ethenoadenine (in vitro), Has strong preference for double-stranded DNA, Has low efficiency with single-stranded substrates, Requires molecular oxygen, alpha-ketoglutarate and iron.
应用类型
WB
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-261 of human ALKBH2 (NP_001138847.1).