Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This gene encodes an aquaporin which functions as a molecular water channel protein. It is a homotetramer with 6 bilayer spanning domains and N-glycosylation sites. The protein physically resembles channel proteins and is abundant in erythrocytes and renal tubes. The gene encoding this aquaporin is a possible candidate for disorders involving imbalance in ocular fluid movement. Several transcript variants encoding different isoforms have been found for this gene.
应用类型
IF,IHC,WB
免疫原
A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human Aquaporin-1 (Aquaporin-1 (AQP1) ) (NP_932766.1).
