May act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2, Part of the WAVE complex that regulates lamellipodia formation, The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex, Regulates ABL1/c-Abl-mediated phosphorylation of MENA, As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity).
应用类型
WB
免疫原
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human ABI2 (NP_001269854.1).
