Stimulates the ATPase activity of several Hsp70-type chaperones, This ability is enhanced by iron-binding, The iron-bound form is redox-active and can function as electron carrier, Plays a role in the diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta).
应用类型
WB
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 2-149 of human DNAJC24 (NP_859057.4).
