The protein encoded by this gene forms part of the nucleosome-associated complex and is important for kinetochore assembly. It is bound to kinetochores during S phase and G2 and recruits other proteins to the centromere. Pseudogenes of this gene are located on chromosome 2. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
应用类型
WB
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 180-300 of human CENPN (NP_001094094).