The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes.
应用类型
WB
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 250-500 of human Dot1L/KMT4 (NP_115871.1).