Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2.
应用类型
该Anti-AK2 antibody产品的应用类型详情查看产品说明书。
免疫原
A synthetic peptide of human AK2
来源宿主
rabbit
反应性
该Rabbit IgG polyclonal antibody for Adenylate kinase 2, mitochondrial(AK2) detection. Tested with WB, IHC, ICC/IF, FCM in Human;Mouse;Rat.产品的反应性详情查看产品说明书。
