This gene encodes a conserved protein that is involved in the repair of DNA interstrand cross-links. DNA cross-links suppress transcription, replication, and DNA segregation. The encoded protein is a regulator of the mitotic cell cycle checkpoint. Alternative splicing results in multiple transcript variants.
应用类型
WB
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human DCLRE1A (NP_001258745.1).