The protein encoded by this gene is a member of the RecQ DEAH helicase family and interacts with the BRCT repeats of breast cancer, type 1 (BRCA1). The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1). This gene may be a target of germline cancer-inducing mutations.
应用类型
WB
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human BRIP1 (NP_114432.2).