Anti‐Cytokeratin (CAM 5.2) reagent has a primary reactivity with human keratin proteins that correspond to Moll`s peptides #7 and #8, MW 48 and 52 kDa, respectively. Cytokeratin 7 and 8 are present on secretory epithelia of normal human tissue but not on stratified squamous epithelium. Anti‐Cytokeratin (CAM 5.2) stains most epithelial‐ derived tissue, including liver, renal tubular epithelium, and hepatocellular and renal cell carcinomas. Anti‐Cytokeratin (CAM 5.2) may not react with some squamous cell carcinomas.