This gene encodes a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. Multiple alternatively spliced transcript variants have been found for this gene.
应用类型
WB
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human DCAF11 (NP_079506.3).