Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function, Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules, The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1, May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores
应用类型
IHC,WB
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human DYNC1I1 (NP_001129028.1).
