The protein encoded by this gene interacts with signaling pathways to coordinately regulate cell growth, cell proliferation, apoptosis, autophagy, and cell migration. This tumor suppressor also enhances retinoblastoma 1 gene expression in cancer cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
应用类型
WB,ELISA
免疫原
Purified recombinant fragment of human RB1CC1 (AA: 148-244) expressed in E. Coli.
