Isoform 2 may participate in the regulation of nucleoplasmic coilin protein interactions in neuronal and transformed cells.nIsoform 3 can regulate global protein synthesis by altering nucleolar numbers. nIsoform 4 may play a role as a modulator of APP processing. Overexpression can down-regulate APP processing.
应用类型
ELISA,IF,IHC,WB
免疫原
ankyrin repeat and sterile alpha motif domain containing 1B