Efficiently catalyzes the reduction of progesterone, androstenedione, 17-alpha-hydroxyprogesterone and testosterone to 5-beta-reduced metabolites. The bile acid intermediates 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one and 7-alpha-hydroxy-4-cholesten-3-one can also act as substrates.
应用类型
ELISA,WB
免疫原
aldo-keto reductase family 1, member D1(delta 4-3-ketosteroid-5-beta-reductase)