GTPase-activating protein(GAP) for ADP ribosylation factor 6(ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.
应用类型
ELISA,IHC,WB
免疫原
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1