Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor(GEF) which plays a role in the activation of Rho GTPases RAC1, RhoA and CDC42. Can regulate cell morphology in cooperation with activated RAC1. Plays a role in Th2(T helper cells) development and/or activation, perhaps by interfering with ZAP70 signaling(By similarity).
