Component of the cleavage and polyadenylation specificity factor(CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Involved in the histone 3' end pre-mRNA processing.
应用类型
ELISA,IF,IHC,WB
免疫原
cleavage and polyadenylation specific factor 2, 100kDa
