CD62L (L-selectin) is an adhesion glycoprotein that is constitutively expressed on the cell surface of leukocytes and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in activation-induced neutrophil aggregation. Activation-dependent CD62L shedding, however, counteracts neutrophil rolling. CD62L has also signaling roles including enhance of chemokine receptor expression. Similarly to CD62P, the major ligand of CD62L is PSGL-1 (P-selectin glycoprotein ligand-1).
应用类型
FC
免疫原
Peripheral blood leukocytes
来源宿主
该Rabbit IgG polyclonal antibody for CD48 antigen(CD48) detection. Tested with WB in Human.产品的来源宿主详情查看产品说明书。