CD84 is a highly glycosylated homophilic receptor of SLAM family. It is expressed on platelets and various types of leukocytes, especially following their activation. Ligation of CD84 leads to its phosphorylation on tyrosine residues within the cytoplasmic tail. These docking sites are recognized by downstream signaling molecules, such as phosphatase SHP-2 and adaptor protein SAP/SH2D1A. The function of CD84 has not been fully elucidated yet. Although predominantly activating receptor, its modulating activity was also demonstrated.
应用类型
FC
免疫原
CD84-transfected 300.19 cell line
来源宿主
该Rabbit IgG polyclonal antibody for Macrosialin(CD68) detection. Tested with WB, IHC in Human.产品的来源宿主详情查看产品说明书。
