Heart-type fatty acid binding protein(hFABP) also known as mammary-derived growth inhibitor is a protein that in humans is encoded by the FABP3 gene. The intracellular fatty acid-binding proteins(FABPs) belongs to a multigene family. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is also a candidate tumor suppressor gene for human breast cancer. Cardiac-type fatty acid-binding protein(cFABP) from human heart muscle of three individuals was isolated and characterized as pI 5.3-cFABP.
应用类型
IHC,WB
免疫原
A synthetic peptide corresponding to a sequence at the C-terminus of human FABP3 (119-133aa THGTAVCTRTYEKEA), different from the related mouse and rat sequences by three amino acids.
