Lyophilized pegylated recombinant rat leptin although stable at room temperature for several weeks, should be stored desiccated below -18 degree C. Upon reconstitution of pegylated recombinant rat leptin at > 0.1 mg/ml and up to 2 mg/ml and filter sterilization pegylated recombinant rat leptin can be stored at 4 degree C or even room temperature for several weeks making it suitable for long term infusion studies using osmotic pumps. At lower concentration of pegylated recombinant rat leptin addition of a carrier protein (0.1% HSA or BSA) is suggested. Please prevent freeze-thaw cycles.