Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion.
应用类型
WB,IHC-P,FC
免疫原
Purified recombinant fragment of human Metadherin expressed in E. Coli.