The activated kinase acts on a variety of targets. Phosphorylates ribosomal protein S6, histone H4 and myelin basic protein. Full length PAK 2 stimulates cell survival and cell growth. The process is, at least in part, mediated by phosphorylation and inhibition of pro-apoptotic BAD.
应用类型
WB,IHC-F,IHC-P,ICC/IF
免疫原
Purified recombinant fragment of PAK2 expressed in E. Coli.
