APP a cell surface receptor that influences neurite growth, neuronal adhesion and axonogenesis. Cleaved by secretases to form a number of peptides, some of which bind to the acetyltransferase complex Fe65/TIP60 to promote transcriptional activation.
应用类型
WB,ICC/IF,IP
免疫原
A synthetic phosphopeptide corresponding to residues surrounding Thr743 of human Amyloid Precursor Protein