H3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.
应用类型
WB,IHC-F,IHC-P,ICC/IF
免疫原
A synthetic phosphopeptide corresponding to residues surrounding Ser28 of human Histone H3
