- 中文名称
Human IgG AccuSignal ELISA Kit - KAA9102
- 英文名字
- Human IgG AccuSignal ELISA Kit - KAA9102
- 供应商
- Rockland
- 产品货号
- KAA9102
- 产品报价
- ¥询价/1Kit
- 产品说明书
- 点击查看
- 购买方式
- 90%产品中国有现货库存。银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- Immunoglobulin G (IgG) is the most abundant protein in the serum which accounts for 75% of the total immunoglobulins in the plasma of healthy individuals. IgG is a major effector molecule of the humoral immune response in humans and provides defense against parasitic invasion. IgG molecules (Fc portion) react with Fc-gamma receptors that are present on the surfaces of macrophages, neutrophils, natural killer cells, and can activate the complement system. IgG is produced in a delayed response to an infection and can be retained in the body for a long time. IgG is the major class of the five classes of immunoglobulins (IgM, IgD, IgG, IgA, and IgE) in human beings. These closely related glycoproteins, composed of 82–96% protein and 4–18% carbohydrate, differ in heavy chain structure and have unique profile with respect to antigen binding, immune complex formation, complement activation, triggering of effector cells and placental transport. IgG can be further divided into four subclasses, IgG1, IgG2, IgG3, and IgG4, based on their relative prevalence in human serum. The IgG concentration in normal human serum ranges from 6 mg/ml to 18 mg/ml. The relative abundance of the different immunoglobulin classes is generally constant in mature adults. Changes in the relative abundance of the different classes typically specify immunological disorders or disease states. For example, congenital and acquired immunodeficiency leads to significantly reduced levels of IgG, while hepatitis, cirrhosis, and most autoimmune diseases increase the levels of IgG. Thus, an accurate quantitation of IgG in plasma or serum is essential for diagnostic studies, as well as for monitoring the efficacy of treatment regimens.
- 产品描述
- Human IgG ELISA kit is designed for the quantitative detection of human IgG in serum, plasma, and hybridoma cell supernatants.
- 产品特点
- 该Human IgG AccuSignal ELISA Kit - KAA9102的详细信息查看Rockland提供的产品说明书。
- 保存建议
- See kit insert for component storage conditions. Store coating buffer, wash buffer, blocking buffer, standard, and reagent diluent at 4˚C. Store substrate solution at 4°C prior to opening. Protect from moisture and light. Store detection antibody and SA-HRP conjugate vial at 4° C prior to restoration. For extended storage aliquot contents and freeze at -20° C or below. Aliquot capture antibody and target protein standard contents and freeze at -20˚C. Avoid multiple freeze-thaw cycles.
- 其他
- Rockland成立于1962年,是一家老牌抗体原产企业,其位于美国费城郊区的农场保有近20种实验动物。Rockland公司为生命科学领域提供丰富的、高质量的抗体,包括载脂蛋白、细胞周期/凋亡、细胞因子、细胞信号蛋白、酶类、细胞外基质、转录因子(NFkB)和泛素(Ubiquitin)等识别抗体,应用范围包括Western blot、免疫组化、免疫荧光和ELISA等。另外,Rockland也生产特别齐全的二抗,包括纯化、生物素、HRP/ALP、荧光标记二抗,应用十分广泛。
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- 注意
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该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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