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细胞分析试剂盒
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中文名称

EZScreen™β-内酰胺酶活性比色分析试剂盒(384孔)

英文名字
EZScreen™ Beta-Lactamase Activity Colorimetric Assay Kit (384-well)
供应商
Biovision
产品货号
K954-400
产品报价
¥询价/400assays
产品说明书
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产品描述
Beta-Lactamases (βLs), are a large family of hydrolases comprising more than 850 identified members expressed in Gram-positive and Gram-negative bacteria. βLs can be classified according to their substrate or inhibitor specificity. These enzymes are capable of hydrolyzing four atom rings known as β-lactams. Antibiotics containing β-lactam rings (i.e. penicillin, cephalosporin, monobactam, carbapenem) are highly susceptible to be hydrolyzed via enzymatic activity, which deactivates their antibiotic potency. βLs have become a significant clinical threat due to the alarming number of cases of bacterial strains showing β-lactam antibiotic resistance. Approaches for combatting this type of resistance have opened up the possibility of developing a new form of β lactam antibiotics that are more resistant to β-Lactamase enzymatic activity. Therefore, experimental research has been arising in wide extent for developing new drugs or inhibitors effective against the β-lactam antibiotic resistance bacteria. BioVision’s EZScreenTM Beta-Lactamase Activity Assay Kit offers a simple and sensitive assay that can detect and quantify the enzymatic activity of these hydrolases. The assay is based on the hydrolysis of Nitrocefin, a chromogenic cephalosporin, that results in the generation of a colored product (OD: 490 nm), which is directly proportional to the amount of βL activity. The assay can detect enzymatic activity as low as 15 mU in a variety of biological samples
产品特点
• Rapid, simple & sensitive • The assay can detect enzymatic activity as low as 15 mU in a variety of biological samples
保存建议
-20
其他
BioVision的公司总部在美丽的旧金山湾地区,它是全球生命科学公司的领导者.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品,以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理,艾美捷与BioVision一起为研究者们提供最好、最新的细胞生物学研究工具而不断扩大产品及服务质量.
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