- 中文名称
PicoProbeTM磷脂酰肌醇测定试剂盒（荧光法）
- 英文名字
- PicoProbeTM Phosphatidylinositol Assay Kit (Fluorometric)
- 供应商
- Biovision
- 产品货号
- K750-100
- 产品报价
- ￥询价/100assays
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868.
- 产品新闻
- 背景资料
- 待更新
- 产品描述
- Phosphoinositides are critical second messengers in a multitude of cellular processes. The most fundamental phosphoinositide, phosphatidylinositol (PI), can be phosphorylated at multiple sites around its inositol ring, leading to downstream activation. For instance, phosphatidylinositol 4-[mono]phosphate is involved in membrane trafficking, while cleavage of phosphatidylinositol triphosphate yields inositol triphosphate, a molecule involved in calcium signaling. Signaling is conveyed in many signaling proteins (including Protein Kinase B/Akt) via their domain referred to as a Pleckstrin homology, or PH domain, which is capable of binding to specific phosphoinositides. Biosynthesis of PI involves the action of phosphatidylinositol synthase on cytidine diacylglycerol and myo-inositol. The critical signal transducer enzymes, Phosphatidylinositolinositol-3-kinases phosphorylate PI at the 3 position hydroxyl of inositol, leading to modulation in pathways such as cell growth, survival, and motility. PI is typically at concentrations in the low- to mid-micromolar range in human serum and plasma, and is capable of activating second messengers such as Ca2+ and cyclic AMP. It is through these pathways that PI has been found to affect such biological events as the pro-inflammatory response and intestinal uptake. BioVision’s Phosphatidylinositol Assay Kit utilizes specific enzymes to generate an intermediate that then reacts with PicoProbeTM, yielding a signal that can be quantified fluorometrically, and is proportional to the amount of PI present in the sample. The assay is capable of detecting as little as 15 pmoles of phosphatidylinositol.
- 产品特点
- This assay provides a convenient and non-ELISA alternative to detect cardiolipin amount in biological samples.,Validated (biological fluids, tissue/cell lysate),Sensitive, Specific
- 保存建议
- -20
- 其他
- BioVision的公司总部在美丽的旧金山湾地区，它是全球生命科学公司的领导者.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品，以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理，艾美捷与BioVision一起为研究者们提供最好、最新的细胞生物学研究工具而不断扩大产品及服务质量.
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- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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